Table 1.

|SH-SY5Y viability and toxicity following treatment with ApoE2/3/4 in vitro. Human neuroblastoma cell line (SH-SY5Y) was grown in vitro and treated for 24 h with 100 μM cholesterol (control) with or without recombinant ApoE2/3/4 (20 nM). Following treatment, cellular viability was measured using MTS and cellular release of lactate dehydrogenase (LDH) was assessed as a measure of cellular toxicity. Data are represented as percent change versus control Mean ± SEM, N = 3, * p < 0.05 vs. Control, ** p < 0.01 vs. Control, ^^^ p < 0.001 vs. ApoE2, ^### p < 0.001 vs. ApoE3.

Treatment Group	ApoE2	ApoE3	ApoE4
Cellular Viability (MTS)	+14.9 ± 0.663 **	+9.7 ± 2.780	−9.7 ± 4.202 ^^^,###
Cellular Toxicity (LDH)	+2.6 ± 3.046	+2.7 ± 4.156	+14 ± 4.164 *