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. 2021 Sep 8;43(2):1133–1141. doi: 10.3390/cimb43020080

Table 2.

Functional categories of up-regulated genes in chromosome 1q21.

Cell Line Genes and GenBank Accession No. Functional Category
H1299 histone 2, H2ab (HIST2H2AB) [NM_175065] Member of the histone H2A family
S100 calcium binding protein A16 (S100A16) [NM_080388] *
hypothetical protein LOC200030 (LOC200030) [NM_183372] *
hypothetical protein DJ328E19.C1.1 (DJ328E19.C1.1) [NM_015383] *
phosphoprotein enriched in astrocytes 15 (PEA15) [NM_003768] Insulin resistance in glucose uptake
histone 2, H2aa (HIST2H2AA) [NM_003516] Member of the histone H2A family
hypothetical protein LOC200030 (LOC200030) [NM_183372] *
histone 2, H2be (HIST2H2BE) [NM_003528] Member of the histone H2B family
histone 2, H2ac (HIST2H2AC) [NM_003517] Member of the histone H2B family
small protein effector 1 of Cdc42 (SPEC1) [NM_020239] *
hypothetical protein FLJ20519 (FLJ20519) [NM_017860] *
MCF7 Notch homolog 2 (Drosophila) N-terminal like (NOTCH2NL), [NM_203458] *
cDNA FLJ11946 fis, clone HEMBB1000709 [AK022008] *
late cornified envelope 2C (LCE2C) [NM_178429] *
S100 calcium binding protein A8 (S100A8) [NM_002964] Cell cycle, progression and differentiation
BI026064 CM0-MT0374-060201-774-h11 MT0374 [BI026064] *
small proline-rich protein 3 (SPRR3), transcript variant 1 [NM_005416] *
small proline-rich protein 1A (SPRR1A) [NM_005987] *
S100 calcium binding protein A9 (S100A9) [NM_002965] Inhibition of casein kinase
cathepsin S (CTSS) [NM_004079] Degradation of the antigenic proteins to peptides on MHC class II
S100 calcium binding protein A3 (S100A3) [NM_002960] *
S100 calcium binding protein A2 (S100A2) [NM_005978] Tumor suppressor function
aquaporin 10 (AQP10) [NM_080429] Water-selective channel

* Genes whose functional categories are unknown.