Key findings made possible by NGS technology

1. Information on the spread of SARS-CoV-2 into and across national borders [47,48,50] and identification of the emergence of distinct viral clades throughout the world [50].

2. Mutational rates and characteristics of distinct regions of the SARS-CoV-2 genome [49,50,52].

3. Information on important individual mutations that have an outsized impact on the continued spread of the virus including the D614G and P323L mutations [50,51].

4. Analysis of intra-host SARS-CoV-2 variants [53].

5. Implications of specific human genotypes on susceptibility to developing severe symptoms made possible by human genome sequencing [54].