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. 2021 Oct 28;43(3):1828–1843. doi: 10.3390/cimb43030128

Figure 8.

Figure 8

Losartan regulated macrophage polarization in liver. (A) Representative CD11b, CD11c, CCR7, CD163, and CD206 staining of liver. Red arrow highlights the positive staining. Scale bar: 100 μm. Tissue staining, as quantified by either stain intensity, is represented on the left-hand vertical axis in each graph. (B) Quantification of CD11c, CCR7, CD206, and CD163 protein levels by Western blot of liver. Below graphs indicate quantification relative to β-actin. Ratio of CD11c/CD206 and CCR7/CD163 in liver. For each animal group, n = 5. All values represent the mean ± SEM. Data were analyzed by Student’s t test. * p ≤ 0.05, normal vs. ob/ob; # p ≤ 0.05, ob/ob vs. ob/ob + Losartan.