Figure 3.

Effect of resveratrol on inflammatory cytokine expression in pro-inflammatory cytokine-stimulated ARPE-19 cells. Cells were pretreated with pro-inflammatory agents (TNF-α, IL-6, and IL-1β alone and in combinations) for 10 min and subsequently treated with 0.125–2 μg/mL of resveratrol for 2 h. (A) IL-6, (B) MCP-1, and (C) IL-8 levels were measured by ELISA. The values represent the mean ± SD of triplicate determinations from three independent experiments. * p < 0.05 indicates significant differences between combinations of pro-inflammatory agents and resveratrol.