Table 2.
Compounds | Rotatable Bonds | MW (<500) | ALog P (≤5) | H-Bond Donor (≤5) | H-Bond Acceptor (≤10) | Rule of 5 Violations |
---|---|---|---|---|---|---|
Yohimbine | 2 | 354.443 | 2.82 | 2 | 5 | 0 |
Abbreviations: MW, molecular weight; LogP, octanol/water partition coefficient.
Compounds | Rotatable Bonds | MW (<500) | ALog P (≤5) | H-Bond Donor (≤5) | H-Bond Acceptor (≤10) | Rule of 5 Violations |
---|---|---|---|---|---|---|
Yohimbine | 2 | 354.443 | 2.82 | 2 | 5 | 0 |
Abbreviations: MW, molecular weight; LogP, octanol/water partition coefficient.