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. 2021 Oct 27;43(3):1805–1827. doi: 10.3390/cimb43030127

Table 2.

Physicochemical properties of yohimbine.

Compounds Rotatable Bonds MW (<500) ALog P (≤5) H-Bond Donor (≤5) H-Bond Acceptor (≤10) Rule of 5 Violations
Yohimbine 2 354.443 2.82 2 5 0

Abbreviations: MW, molecular weight; LogP, octanol/water partition coefficient.