Theoretical activation changes of entropy (ΔS^≠), activation energies (E_a) and pseudo-first-order reaction rate coefficients (k_H2O) for the four reactions in Fig. 9.

Reaction	ΔS≠ (kcal mol−1 K−1)	E a (kcal mol−1)				k H2O (s−1)
		288 K	298 K	308 K	318 K	288 K	298 K	308 K	318 K
3A	−0.039	35.5	35.5	35.5	35.6	8.4 × 10−20	1.3 × 10−18	1.7 × 10−17	1.8 × 10−16
3B	−0.047	36.6	36.6	36.7	36.7	1.9 × 10−22	3.6 × 10−21	5.6 × 10−20	7.3 × 10−19
3C	−0.047	33.7	33.7	33.8	33.8	3.3 × 10−20	5.3 × 10−19	7.2 × 10−18	8.4 × 10−17
3D	−0.048	34.7	34.8	34.8	34.8	2.4 × 10−21	4.2 × 10−20	6.2 × 10−19	7.7 × 10−18