TABLE 1.
Characteristics of 64 patients with culture-positive typhoid fever before treatment
| Parameter | Azithromycin | Ciprofloxacin |
|---|---|---|
| No. of patients treated | 36 | 28 |
| Age (yrs) | ||
| Range | 18–30 | 18–32 |
| Mean | 19.6 | 20.3 |
| No. of male | 24 | 19 |
| No. of female | 12 | 9 |
| No. of days of fever before admission | ||
| Range | 3–30 | 3–15 |
| Mean | 9.7 | 9.2 |
| No. of patients with: | ||
| Blood cultures with S. typhi | 34 | 25 |
| Blood or stool cultures with S. typhi showing resistance to ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole | 6 | 15 |
| Blood cultures with S. paratyphi A | 1 | 2 |
| Stool cultures with: | ||
| S. typhi | 4 | 7 |
| S. paratyphi A | 1 | 0 |
| Mean laboratory value ± SD (normal range) | ||
| Hemoglobin (11–18 g/100 ml) | 11.6 ± 2.4 | 12.4 ± 1.9 |
| Hematocrit (35–60%) | 35.1 ± 4.7 | 36.6 ± 5.0 |
| Leukocyte count ([4.5–10.5] × 103/mm3) | 5.44 ± 2.10 | 5.12 ± 1.65 |
| Platelet count ([150–450] × 103/mm3) | 171 ± 78 | 179 ± 72 |
| Bilirubin (0.2–1.0 mg/100 ml) | 0.67 ± 0.32 | 0.58 ± 0.26 |
| AST (5–49 IU) | 69.2 ± 43.4 | 87.1 ± 106.8a |
| Blood urea nitrogen (7–18 mg/100 ml) | 16.4 ± 16.4b | 12.4 ± 5.9 |
| Creatinine (0.7–1.5 mg/100 ml) | 0.97 ± 0.54 | 0.91 ± 0.31 |
a
One patient had a value of 527 IU, and one had 310 IU, causing the mean and standard deviation to be high.
b
One patient had a value of 87 mg/100 ml, and one had 70 mg/100 ml, causing the standard deviation to be high.