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Schematic representation illustrating the progression of SARS‐CoV‐2‐mediated COVID‐19 disease from mild or asymptomatic infection to either full recovery or serious illness. Highlighted is viral self‐assembly at scale and population spread is mediated by upper respiratory tract infection. The fundamental pathophysiology of serious COVID‐19 disease is driven by lower respiratory tract infection and does not favor viral self‐assembly at scale
