FIGURE 2.

PF‐06767832 reduces alcohol self‐administration. (A) Schematic of experimental timeline. PF‐06767832 (PF ‘832; 1 mg/kg i.p) (B) decreases alcohol self‐administration on the active, but not an inactive lever. (C) Timecourse reveals a decrease at the 10 min time point. (D) No difference in latency to first lever press was observed in rats that received PF’832. (E) The reduction in alcohol self‐administration induced by PF ‘832 was not observed 24 h following administration. Data expressed as mean ± SEM, n = 16. TBC: two‐bottle choice; FR3: fixed ratio 3. Open circle = active lever, closed circle = inactive lever. Created with BioRender.com