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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: J Neuropsychiatry Clin Neurosci. 2021 Aug 16;33(4):356–364. doi: 10.1176/appi.neuropsych.20120316

Table 2:

Differentiating features of delirium from “pseudodelirium”

DELIRIUM DISORGANIZED PSYCHOSIS GANSER SYNDROME DELIRIOUS MANIA PRIMARY CATATONIA
EEG Diffuse slowing No specific pattern Typically normal Unknown Typically normal
Clinical status Sick, often frail Medically stable Medically stable Variable; often with autonomic activation Medically stable
Arousal Rarely appropriately alert Alert Fluctuates; may be alert for extended periods Can alternate between hyperkinetic and stuporous Usually stuporous, occasionally hyperkinetic
Interpersonal Inattentive Variable; often difficult to rule out inattention Often engaged Fluctuates; often inattentive Disengaged, negativistic; occasionally automatically obedient
Verbal responses Muddled thinking Speech disorganized Approximate answers common Initially hyperverbal, may devolve to mutism Mute, whispered, verbigeration, or echolalia
Sensorium Clouded Usually clear Verbal content suggests clouding Clouded in mid-to-late stages Often clear but difficult to assess
Emotional state Consistent with motor subtype Often paranoid Effortful engagement Manic, may devolve to blunted state Fearful, occasionally manic
Psychosocial Reduced engagement Difficult to engage Bizarre; psychosocial stressor present May be initially intrusive, then disengaged Variable, related to underlying condition