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. 2021 Nov 10;1(2):100027. doi: 10.1016/j.xgen.2021.100027

Table 1.

VRS Objects

Object type Identifier prefix VRS release Purpose
Variation

Allele VA v1.0 contiguous insertions and deletions at a specific Location
Text VT v1.0 other forms of variation (technical compatibility)
VariationSet VS v1.1 collections of variation
Haplotype VH v1.1 phased molecular variation
CopyNumber VCN v1.2 an absolute systemic quantity/copy number variation
Gene Fusion planned concept for representing deregulated or novel transcripts resulting from gene fusion
Gene Expression planned systemic variation concept for representing gene product abundance
Genotype planned summary of variation corresponding to a Location
Structural Variation planned novel molecules composed from sequence originating at non-contiguous locations

Location

SequenceLocation VSL v1.0 locations on defined IUPAC character sequences
ChromosomeLocation VCL v1.1 locations on defined cytogenetic regions

SequenceExpression

LiteralSequenceExpression N/A v1.2 used to define a specific sequence of literal IUPAC characters
DerivedSequenceExpression N/A v1.2 used to define a sequence described by a sequence location
RepeatedSequenceExpression N/A v1.2 used to define a specific sequence by a number of repeats of an indicated subsequence

Interval

CytobandInterval N/A v1.1 a cytogenetic interval specified using cytoband nomenclature
SequenceInterval N/A v1.2 an interval on a sequence specified by a start and end coordinate or coordinate range.