Table 2:
Comorbidities
| Study cohort (n = 247) | Incidence TMA (n = 11) | Univariable analysis |
||
|---|---|---|---|---|
| P-value | Odds ratio | |||
| S/p stroke or CVA | 46 | 2 (4) | 0.969 | 0.970 (0.202–4.646) |
| Acute kidney injury | 17 | 1 (6) | 0.768 | 1.375 (0.165–11.425) |
| Chronic kidney disease | 29 | 1 (3) | 0.781 | 0.743 (0.092–6.025) |
| LVEF (%) | 60 | 60 (52–60) | 0.695 | 0.986 (0.918–1.059) |
| Coronary artery disease | 63 | 3 (5) | 0.891 | 1.100 (0.283–4.281) |
| Diabetes mellitus | 22 | 1 (5) | 0.983 | 1.024 (0.125–8.293) |
| w/insulin | 5 | 1 (20) | 0.131 | 5.800 (0.593–56.756) |
| Hypertension | 192 | 8 (4) | 0.684 | 0.754 (0.193–2.943) |
| COPD | 19 | 1 (5) | 0.859 | 1.211 (0.147–10.000) |
| Smoker | 85 | 2 (2) | 0.261 | 0.410 (0.086–1.940) |
| Obesity | 53 | 2 (4) | 0.787 | 0.806 (0.169–3.848) |
Data are shown as median (0.25–0.75 percentile), n (%) or odds ratio (95% confidence interval), bold: statistically significant.
COPD: chronic obstructive pulmonary disease; CVA: cerebrovascular accident; LVEF: left ventricular ejection fraction; TMA: thrombotic microangiopathy.