Table 2.
Selected T lymphocyte epitopes (CTL + HTL epitopes) and their corresponding MHC alleles.
| Protein No | CTL Epitopes | MHC I binding Alleles | HTL Epitopes | MHC II binding Alleles |
|---|---|---|---|---|
| 1 | CPIAPGRGA (21) | HLA-B*07:02 | TEQYSGLCPIAPGRG (14) | HLA-DRB1*10:01, HLA-DRB1*01:01, HLA-DRB1*04:01, HLA-DRB1*04:05, HLA-DQA1*02:01/DQB1*03:01, HLA-DQA1*05:01/DQB1*03:02, HLA-DQA1*05:01/DQB1*03:03, HLA-DQA1*02:01/DQB1*03:03, HLADQA1*03:01/DQB1*03:01, HLA-DQA1*05:01/DQB1*04:02 |
| 2 | TGLAVLDLY (43) DLVLADPPY (114) | HLA-A*30:02 HLA-B*35:01, HLA-A*29:02, HLA-B*15:02 | WPQRVYGDTRLELAE (168) | HLA-DRB1*03:01, HLA-DPA1*03:01/DPB1*04:02, HLA-DPA1*02:01/DPB1*01:01, HLA-DPA1*01:03/DPB1*02:01 |
| ARNIEALGL (83) | HLA-B*27:05 | |||
| 3 | NMAQTDSAV (81) | HLA-B*18:01 | RNFQVIYEQANAHGQ (59) | HLA-DRB4*01:01, HLA-DRB1*10:01, HLA-DRB1*04:01, HLA-DRB1*08:02, HLA-DQA1*01:02/DQB1*05:01, HLA-DRB1*01:01, HLA-DRB1*04:05, HLA-DRB1*16:02, HLA-DRB5*01:01, HLA-DRB3*03:01, HLA-DRB1*15:01 |
| YEQANAHGQ (65) | HLA-A*02:06 | |||
| 4 |
IRESASQAL (217) EVNPEPTPL (201) |
HLA-B*39:01, HLA-C*07:01 HLA-C*03:03, HLA-A*68:02, HLA-C*15:02 | ||
| 5 | MTEQQWNFA (1) | HLA-A*01:01, HLA-A*68:02, HLA-A*30:01 | ||
| WGGSGSEAY (49) | HLA-B*35:01, HLA-A*29:02 | |||
| 6 | GELADVDVGI (298) | HLA-B*40:01, HLA-A*02:01, HLA-A*68:02 | DLFMLRQIHFAPRLT (409) | HLA-DPA1*01:03/DPB1*06:01, HLA-DRB1*13:01, HLA-DRB4*01:03, HLA-DQA1*05:01/DQB1*04:02, HLADRB5*01:01, HLA-DRB1*08:01, HLA-DRB1*10:01, HLA-DRB4*01:01, HLA-DPA1*01:03/DPB1*04:01, HLA-DRB1*11:01, HLA-DRB1*01:01, HLA-DRB1*12:01, HLA-DPA1*03:01/DPB1*04:02, HLA-DRB3*03:01, HLA-DRB1*15:01, HLA-DQA1*03:03/DQB1*04:02, HLA-DRB1*04:04, HLA-DPA1*01:03/DPB1*03:01, HLA-DPA1*02:01/DPB1*01:01, HLA-DRB1*07:01, HLA-DRB1*09:01, HLA-DQA1*01:02/DQB1*05:01, HLA-DRB1*16:02, HLA-DRB1*04:01, HLA-DQA1*06:01/DQB1*04:02, HLA-DPA1*01:03/DPB1*02:01, HLADRB1*13:02, HLA-DQA1*01:02/DQB1*05:02, HLA-DRB1*04:05, HLA-DQA1*02:01/DQB1*04:02, HLADRB3*02:02, HLA-DRB1*08:02 |
| HLGYKCSIRK (388) | HLA-A*03:01, HLA-A*11:01 | CRAAWLTLRDRRTKR (535) | HLA-DRB4*01:03, HLA-DRB1*13:01, HLA-DQA1*02:01/DQB1*04:02, HLA-DRB5*01:01, HLA-DRB1*11:01, HLA-DRB1*01:01, HLA-DRB1*08:01, HLA-DQA1*05:01/DQB1*04:02, HLA-DRB1*03:01, HLADQA1*06:01/DQB1*04:02, HLA-DRB1*16:02, HLA-DRB1*10:01, HLA-DQA1*03:03/DQB1*04:02, HLA-DRB1*04:05, HLA-DRB3*03:01 | |
| 7 | RLLFVSPRI (3) | HLA-A*32:01, HLA-A*02:01, HLA-A*02:06, HLA-A*30:01 | ||
| SLNLSNAAAV (130) | HLA-A*02:01, HLA-A*02:06 | |||
| 8 | FTLTVGLML (142) | HLA-A*02:06, HLA-C*15:02, HLA-A*02:01, HLA-C*03:03, HLA-C*14:02 | ||
| GLVAADLVL (118) | HLA-A*02:01, HLA-B*15:01 | |||
| IRLPGRPFRV (87) | HLA-A*02:01, HLA-B*27:05 |