Table 1.
Included Manuscripts and Study Characteristics
| Study | Type of Study | Location | Centers | Study Period | No. patients | Facial Regions | Facial Feminization Surgeries | Average No. FFS Per Patient | Average Follow-up Period |
|---|---|---|---|---|---|---|---|---|---|
| Balaji9 | Prospective | India | Single center | 2007–2014 | 7 | Upper, middle, lower | Forehead reconstruction, rhinoplasty, genioplasty, gonial angle reduction, jaw contouring, zygoma correction | Multiple | — |
| Becking et al.10 | Retrospective | The Netherlands | Single center | 1992–1994 | 16 | Middle, lower | Bimaxillary osteotomy, gonial angle reduction, genioplasty, zygoma augmentation, zygoma osteotomies | 1.3 | — |
| Bellinga et al.11 | Retrospective | Spain | Single center | 2010–2015 | 200 | Upper, middle, lower | Rhinoplasty, forehead reconstruction, lip lift | 2.1 | 18.8 mo |
| Capitán et al.12 | Retrospective | Spain | Single center | 2008–2014 | 214 | Upper, lower | Forehead reconstruction, genioplasty, gonial angle osteotomy, jaw recontouring | 1.8 | 28 mo |
| Capitán et al.13 | Retrospective | Spain | Single center | 2012–2015 | 65 | Upper | Forehead reconstruction, hair transplantation | 2 | 26 mo |
| Chou et al.14 | Retrospective | The United States | Single center | 2016–2018 | 121 | Upper, middle, lower, neck | Scalp advancement, cranioplasty, brow lift, rhinoplasty, upper lip lift, mandibuloplasty, chondrolaryngoplasty | 4.9 | 2.2 mo |
| Garcia-Rodriguez et al.15 | Retrospective | The United States | Single center | 2018 | 29 | Upper | Hairline advancement, brow lift, galeotomy, frontal cranioplasty | Multiple | — |
| Gupta et al.16 | Retrospective | The United States | Single center | 2005–2017 | 25 | Upper, middle, lower | Rhytidectomy, forehead contouring, cheek implants, rhinoplasty, mandible contouring | 3 | 5.2 mo |
| Hoenig17 | Retrospective | Germany | Single center | 36-mo period | 21 | Upper | Frontal cranial vaultplasty | 1 | 18 mo |
| Hage et al.18 | Retrospective | Netherlands | Single center | 1985–1996 | 22 | Middle | Rhinoplasty | 1 | 30 mo |
| Khafif et al.19 | Prospective | Israel | Single center | 2019 | 4 | Neck | Chondrolaryngoplasty | 1 | 2 mo |
| La Padula et al.20 | Retrospective | France | Single center | 2015–2018 | 25 | Upper, middle, lower, neck | Frontal bone grinding, hairline advancement, rhinoplasty, malar implant, malar osteotomy, facial lipofilling, mandibular angle grinding, masseter muscle resection, mandibular angle implants, upper lip lift, orthognathic surgery, genioplasty, cervical liposuction, reduction laryngoplasty | 7.6 | — |
| Lipschitz et al.21 | Retrospective | Israel | Single center | 2006–2015 | 27 | Neck | Thyroid chondroplasty, cricothyroid approximation | 1.6 | 2.7 mo |
| Morrison et al.8 | Prospective | The United States | Multicenter | — | 66 | Upper, middle, lower, neck | Hairline lowering, hair transplantation, brow contouring, brow/frontal sinus setback, genioplasty, mandibular contouring, rhinoplasty, thyroid cartilage reduction, lip lift, brow lift, face lift, otoplasty, blepharoplasty, fat grafting | 4.2 | — |
| Raffaini et al.22 | Retrospective | Italy | Single center | 2003–2013 | 33 | Upper, middle, lower, neck | Rhinoplasty, mandibular reshaping, genioplasty, orthognathic surgery, frontal bone reshaping, tracheal shave, midface lift, liposuction of neck, fat grafting to lip and zygoma, prosthesis removal | 5.5 | 24 mo |
| Raffaini et al.23 | Retrospective | Italy | Single center | 2003–2017 | 9 | Upper, middle, lower, neck | Mandible contouring, genioplasty, chin osteotomy, lipofilling of lips, frontal bone grinding, brow lift, canthoplexy, scalp advancement, rhinoplasty, malar/cheek lipofilling, laryngochondroplasty, cervical fat removal | Multiple | 15 mo |
| Salgado et al.24 | Retrospective | The United States | Single center | — | 4 | Upper, middle | Frontal bone reduction, reduction rhinoplasty | 2 | 21 mo |
| Shams and Motamedi25 | Retrospective | Iran | Single center | 1990–2007 | 10 | Upper, middle, lower, neck | Reduction genioplasty, total mandibular angle and body reduction, maxillomandibular osteotomy, zygoma advancement, reduction rhinoplasty, forehead feminization, chondroplasty | 6 | — |
| Tang26 | Retrospective | The United States | Multicenter | 2016–2020 | 91 | Neck | Laryngochondroplasty | 1 | 20.7 mo |
| Tawa et al.27 | Prospective | France | Single center | 2018–2019 | 45 | Upper, lower | Frontal bone osteotomy, mandibular osteotomy, genioplasty | 3 | 5.1 mo |
| Telang28 | Retrospective | India | Single center | 2016–2019 | 220 | Upper, middle, Lower, neck | Forehead contouring, orbital shave, hairline advancement, rhinoplasty, blepharoplasty, cheek augmentation, jaw shave, gonial angle shave, chin reduction, tracheal shave, lip lift and augmentation, neck lift | 6.3 | 40 mo |
| Villepelet et al.,29 | Retrospective | France | Single center | 2011–2014 | 8 | Upper | Frontal remodeling, orbital remodeling, canthopexy | 1 | 12.4 mo |
Describes type of study, patient cohort size, facial procedures described, and average number of procedures performed per patient. Twenty-two studies were included reporting a range of 4 to 220 patients.