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. 2022 Mar 17;17(3):e0265486. doi: 10.1371/journal.pone.0265486

Fig 1. No differences in ligature-induced bone-loss between Tcrd-H2BeGFP, Tcrd–/–and IL17af–/–mice with or without presence of P. gingivalis.

Fig 1

(A) scheme of the procedure applied to induce periodontitis. (B) Scheme of the bone-loss-analysis by measuring the CEJ-ABC distance (left) or the area laying open between CEJ and ABC (right). (C) CEJ-ABC distance and representative raw-data of defleshed jaws after methylene blue staining. Each point represents a mouse. Data were statistically analyzed by Kruskal-Wallis test, mean and SD are shown. (D) CEJ-ABC area and representative raw-data of defleshed jaws after methylene blue staining. Each point represents a mouse. Data were obtained from three independent experiments and statistically analyzed by Kruskal-Wallis test and Dunn´s multiple comparisons, mean and SD are shown. A p‐value below 0.05 was considered as significant. All genotypes show statistically significant bone loss compared to control, which is not depicted in the figure.