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. 2022 Mar 17;19(3):e1003941. doi: 10.1371/journal.pmed.1003941

Fig 3. HRs, 95% CIs, and p-values for the association of lithium with the development of dementia (and its subtypes) by Cox proportional hazards models.

Fig 3

HRs, 95% CIs, and p-values were extracted from inverse probability weighted Cox regression. Adjusted HRs were adjusted for age, sex, marital status, ethnicity, smoking status, alcohol disorders, antipsychotic use, depression, mania or BPAD, hypertension, central vascular disease, diabetes mellitus, and hyperlipidemias. The AIC was 14,275 for the model fitted for all dementias, 13,240 for the model fitted for AD, and 13,220 for the model fitted for VD. AD, Alzheimer disease; AIC, Akaike information criterion; BPAD, bipolar affective disorder/mania; CI, confidence interval; HR, hazard ratio; VD, vascular dementia.