Table 4. Fasted serum concentrations of glucose, cholesterol, NEFA, TAG, LDL, VLDL, HDL-C, ALT, and ALP of post-gonadectomy kittens supplemented with additional choline at 300 mg/kg BW0.75 (CHOLINE, n = 8) compared to a group fed only the base diet (CONTROL, n = 7) over 12 weeks.
Week | CHOLINE (n = 8) | CONTROL (n = 7) | P-Values | |||||
---|---|---|---|---|---|---|---|---|
LSM | SEM | LSM | SEM | PGroup | PTime | PGroup*Time | ||
Glucose (mmol/L) | -1 | 15.68 | 0.69 | 15.85 | 0.73 | 0.491 | 0.140 | 0.639 |
12 | 14.22 | 15.08 | ||||||
Cholesterol (mmol/L) | -1 | 4.36 | 0.18 | 4.42 | 0.19 | 0.607 | 0.716 | 0.395 |
12 | 4.45 | 4.20 | ||||||
NEFA (mmol/L) | -1 | 0.31 | 0.03 | 0.29 | 0.03 | 0.174 | 0.715 | 0.091 |
12 | 0.26 | 0.37 | ||||||
TAG (mmol/L) | -1 | 0.39 | 0.04 | 0.40 | 0.04 | 0.156 | 0.134 | 0.480 |
12 | 0.43 | 0.50 | ||||||
LDL (mmol/L) | -1 | 1.03 | 0.08 | 1.10 | 0.08 | 0.181 | <0.0001 | 0.151 |
12 | 0.60 | 0.37 | ||||||
VLDL (mmol/L) | -1 | 0.18 | 0.02 | 0.18 | 0.02 | 0.153 | 0.133 | 0.476 |
12 | 0.19 | 0.23 | ||||||
HDL-C (mmol/L) | -1 | 3.13 | 0.17 | 3.13 | 0.18 | 0.209 | 0.002 | 0.212 |
12 | 4.06 | 3.59 | ||||||
ALT (U/L) | -1 | 37.0 | 4.09 | 35.0 | 4.37 | 0.373 | 0.011 | 0.167 |
12 | 43.63 | 53.43 | ||||||
ALP (U/L) | -1 | 95.0 | 8.55 | 100.14 | 9.14 | 0.580 | <0.0001 | 0.726 |
12 | 53.50 | 61.71 |
ALT, Alanine Aminotransferase; ALP, alkaline phosphatase; HDL-C, high-density lipoprotein cholesterol; LDL, low-density lipoprotein; LSM, least square means; NEFA, non-esterified fatty acid; SEM, standard error of the mean; TAG, triacylglyceride; VLDL, very low-density lipoprotein