. 2022 Mar 17;17(3):e0264321. doi: 10.1371/journal.pone.0264321

Table 5. Fasted serum satiety hormone concentrations of post-gonadectomy kittens supplemented with additional choline at 300 mg/kg BW^0.75 (CHOLINE, n = 8) compared to a group fed only the base diet (CONTROL, n = 7) over 12 weeks.

	Week	CHOLINE (n = 8)		CONTROL (n = 7)		P Values
	Week	LSM	SEM	LSM	SEM	P_Group	P_Time	P_Group*Time
Leptin (ng/mL)	-1	4.04	0.32	3.77	0.34	0.946	0.141	0.467
Leptin (ng/mL)	12	3.28	0.32	3.50	0.34	0.946	0.141	0.467
Ghrelin (ng/mL)	-1	15.13	2.58	14.19	2.76	0.804	0.512	0.924
Ghrelin (ng/mL)	12	16.67	2.58	16.24	2.76	0.804	0.512	0.924
GLP-1 (ng/mL)	-1	1.03	0.42	1.08	0.50	0.703	0.981	0.765
GLP-1 (ng/mL)	12	0.90	0.42	1.21	0.50	0.703	0.981	0.765
PYY (ng/mL)	-1	2.48	0.51	1.71	0.61	0.983	0.810	0.179
PYY (ng/mL)	12	1.56	0.51	2.36	0.61	0.983	0.810	0.179
GIP (ng/mL)	-1	286.34	16.67	277.05	17.84	0.220	0.318	0.082
GIP (ng/mL)	12	271.43	16.67	328.26	17.84	0.220	0.318	0.082

GLP-1, glucagon-like peptide-1; GIP, gastric inhibitory polypeptide; LSM, least square means; PYY, Peptide-YY; SEM, standard error of the mean

Table 5. Fasted serum satiety hormone concentrations of post-gonadectomy kittens supplemented with additional choline at 300 mg/kg BW0.75 (CHOLINE, n = 8) compared to a group fed only the base diet (CONTROL, n = 7) over 12 weeks.