Table 1.
ID50 titres against omicron and wild-type SARS-CoV-2 in hospital workers infected with SARS-CoV-2 in early 2020
| Wild-type SARS-CoV-2 ID50 | Omicron ID50 | Fold change in ID50 (wild-type vs omicron) | Self-reported vaccine history* | |
|---|---|---|---|---|
| Individual A | 840 | 43 | 20 | Unknown |
| Individual B | 442 | 213 | 2 | ChAdOx1 and BNT162b2 (4 months) |
| Individual C | 686 | 734 | 1 | Two doses of BNT162b2 (4 months) |
| Individual D | 185 | 79 | 2 | Two doses of BNT162b2 (8 months) |
| Individual E | 879 | 214 | 4 | Two doses of ChAdOx1 (5 months) |
| Individual F | 230 | 10 | 23 | Unknown |
| Individual G | 137 | 17 | 8 | ChAdOx1 and BNT162b2 (4 months) |
| Individual H | 259 | 36 | 7 | Two doses of BNT162b2 (8 months) |
| Individual I | 440 | 179 | 2 | Two doses of ChAdOx1 (4 months) |
| Individual J | 2202 | 549 | 4 | Unknown |
| Individual K | 382 | 207 | 2 | Two doses of ChAdOx1 (5 months) |
| Individual L | 451 | 155 | 3 | Two doses of BNT162b2 (5 months) |
| Individual M | 338 | 36 | 9 | Unknown |
| Individual N | 269 | 16 | 17 | Two doses of BNT162b2 (8 months) |
| Individual O | 3748 | 4053 | 1 | Two doses of BNT162b2 (2 months) |
| Individual P | 291 | 22 | 13 | Two doses of BNT162b2 (4 months) |
| Individual Q | 1166 | 493 | 2 | Unknown |
Age of individuals ranged from 28 to 74 years (median 54 years [IQR 41–62]). ID50=reciprocal serum dilution that produces 50% inhibition.
*
Calendar months between most recent immunisation and day of serum sampling are shown in parentheses.