Table 1.
Glycaemia values, morphometric parameters, and LV cell dimensions
| CTR | STZ | P vs. CTR | |
|---|---|---|---|
| Fasting glycaemia (mg/dL) | 94±2 | 390±14 | * |
| Non-fasting glycaemia (mg/dL) | 126±4 | 560±8 | * |
| BW (g) | 400±7 | 202±6 | * |
| BW gain (g) | 230±14 | 26±8 | * |
| HW (g) | 1.65±0.08 | 1.03±0.03 | * |
| TL (cm) | 4.3±0.02 | 3.63±0.03 | * |
| HW/BW (g/kg) | 4.11±0.17 | 5.16±0.11 | * |
| HW/TL (g/cm) | 0.40±0.03 | 0.28±0.009 | * |
| LVW/HW (%) | 67.9±1.0 | 63.4±0.7 | * |
| KW (g) | 2.23±0.05 | 2.19±0.07 | NS |
| KW/TL (g/cm) | 0.52±0.01 | 0.6±0.02 | * |
| LV cell length (µm) | 136±2.8 | 120±2.1 | * |
| LV cell volume (103 µm3) | 65±1.9 | 37±1.03 | * |
| LV CSA (um2) | 482±13.8 | 309±7.5 | * |
| LV Cm (pF) | 179±6 | 136±4 | * |
BW, Body weight; HW, heart weight; KW, kidney weight; LVW, left ventricular weight; TL, tibia length.
Morphometric parameters: CTR N =15–21, STZ N =23–34. Cell dimensions (length, volume, and CSA): CTR N =4 (n =58), STZ N =6 (n =108). Cell membrane capacitance (Cm): CTR N =12 (n =75), STZ N =13 (n =83).
*P
<0.05 vs. CTR (unpaired t-test).