Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 20;118(4):1115–1125. doi: 10.1093/cvr/cvab139

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Nucleosomes and histone H4 are released from rat hearts subject to ischaemia and reperfusion. (A) Nucleosome concentration in the perfusate of perfused heart measured by ELISA (N = 5 hearts per group). (B) Histone H4 concentration in the perfusate of perfused heart measured by DELFIA. N = 8 hearts per group. (C) Total histone H4 release is correlated to final infarct size (N = 16). Statistical analyses by repeated measures ANOVA followed by Tukey test. **P < 0.01, ***P < 0.001 compared to the measurement taken before reperfusion.