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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 May 27;7(4):415–423. doi: 10.1016/j.bpsc.2021.05.002

Figure 2.

Figure 2.

Seed region and target regions for the tractography analysis. The target regions of the striatum were functionally segmented based on projections to motor, executive, and limbic cortices [from Tziortzi et al. (18)]. The seed region of the midbrain was generated from a probabilistic substantia nigra (SN)/ventral tegmental area (VTA) mask [from Murty et al. (43)]. The probabilistic mask was thresholded at 50% and binarized to create the seed mask for tractography analysis. These masks were then tailored to each subject’s T1-weighted anatomical scan.