Table 2.

Performance of individual indicators or combination models in the detection of HCC from comprehensive control.

Indicator	Cutoffa	AUCb	S.E.	CI 95	Sens.	Spec.	Accu.
AFP	5.54	0.675	0.028	0.625-0.722	0.743	0.552	0.636
CA199	37.44	0.549	0.030	0.498-0.600	0.293	0.849	0.604
Model_1	0.416	0.667	0.028	0.617-0.714	0.623	0.693	0.662
CCL20	117.08	0.742	0.025	0.695-0.785	0.569	0.811	0.704
LCN2	94.92	0.913	0.014	0.881-0.940	0.743	0.943	0.855
Model_2	0.443	0.927	0.012	0.896-0.951	0.808	0.892	0.859

AUC: area under curve; S.E.: standard error; CI 95: 95% confidence interval; Sens.: sensitivity; Spec.: specificity; Accu.: accuracy. ^aCutoff values were calculated according to maximal Youden index; ^bdifferences between AUCs were compared; significance is showed in Supporting Table 3.