Fig. 1 Legend. Frequency of HLA class-I APM Component Defects by Cancer Type.

HLA class-I APM component defect frequency by cancer type was assessed via systematic review of the literature.⁶ A total of 237 papers were identified that analyzed immunohistochemical HLA class-I APM component expression in cancer tissues. Only cancer types in which HLA class-I APM component expression was assessed in at least 100 cases have been included in this heatmap. Combined defect frequency amongst all cancers is shown in the bottom row. Exact proportions of cancers with HLA class-I APM component defects are available in Supplementary Table 1.