REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Please see a detailed list of antibodies used in Table S1
Deposited data
Single cell imaging data	This study	http://doi.org/10.5281/zenodo.4525425.
Experimental models: Cell lines
Retinal pigment epithelial cells (hTERT-RPE-1)	ATCC	CRL-4000
Human pancreatic epithelial cells (hTERT-HPNE)	ATCC	CRL-4023
RPE-PCNA-mTurqoise2	Laboratory of Jeremy Purvis	(Chao et al., 2019)
RPE-p21-mTq2/cycD1-mVenus/DHB-mCherry/H2B-mIFP	Laboratory of Jorg Mansfield	(Zerjatke et al., 2017)
Software and algorithms
StackReg	https://imagej.net/plugins/stackreg	(Thévenaz et al., 1998)
CellProfiler v3.1.8	https://cellprofiler.org/	(McQuin et al., 2018)
caret v6.0–86	https://cran.r-project.org/web/packages/caret/vignettes/caret.html
scikit-learn v0.24	https://scikit-learn.org/stable/
Fastai	https://github.com/fastai/fastai
PHATE	https://github.com/KrishnaswamyLab/PHATE	(Moon et al., 2019)
Leidenalg v0.8.3	https://github.com/vtraag/leidenalg	(Traag et al., 2019)
scanpy v1.6	https://github.com/theislab/scanpy	(Wolf et al., 2018)
singlecellVR	singlecellvr.com	(Stein et al., 2020)