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. Author manuscript; available in PMC: 2022 Aug 17.
Published in final edited form as: Nat Cell Biol. 2022 Feb 17;24(3):373–383. doi: 10.1038/s41556-022-00848-5

Extended Data Fig. 8: AAV-mediated Lsd1 knockout in the liver has little effect on liver size and histology in Lsd1f/f mice.

Extended Data Fig. 8:

a, Wildtype (WT) and Lsd1flox/flox (Lsd1f/f) mouse livers 19 days post AAV8-ApoE/AAT1-Cre treatment, and quantification of liver to body mass ratio. Data are represented as mean ± SD, n = 5, unpaired two-tailed Student’s t-test. b, Western blot analysis of LSD1 expression in WT and Lsd1f/f mouse livers post AAV treatment, and quantitation of relative LSD1 protein levels. Data are shown as mean ± SD, n = 5, unpaired two-tailed Student’s t-test. c, Representative images of liver H&E staining. Livers from 5 mice each experiment were examined with similar results. d, Liver Ki67 IHC staining and quantification. Data are represented as mean ± SD, n = 5, unpaired two-tailed Student’s t-test.