Table 1.
Gating properties of sodium currents recorded from rat DRG neurons.
DMSO (0.1%) | JPH203 (10 μM) | |
---|---|---|
Activation | ||
V 1/2 | −12.925 ± 1.095 (17) | −14.832 ± 1.778 (11) |
k | 8.648 ± 0.999 (17) | 10.015 ± 1.676 (11) |
Inactivation | ||
V 1/2 | −29.851 ± 1.941 (16) | −38.745 ± 2.147 (11)* |
k | −12.605 ± 1.768 (16) | −12.263 ± 2.076 (11) |
Values are means ± SEM calculated from fits of the data from the indicated number of individual cells (in parentheses) to the Boltzmann equation; V1/2 mid-point potential (mV) for voltage-dependent of activation or inactivation; k, slope factor. These values pertain to Fig. 4c and 4d.
Indicate statistical difference compared to the DMSO group (p= 0.0057). Data were analyzed with unpaired t test.