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. Author manuscript; available in PMC: 2023 Mar 16.
Published in final edited form as: Chemistry. 2022 Feb 21;28(16):e202200146. doi: 10.1002/chem.202200146

Scheme 2.

Scheme 2.

Chemical synthesis of the monovalent and multivalent α-Gal-based antibody recruiting molecules. a) 2, DMSO, Et3N, RT, 58%; b) 9, DMSO, Et3N, RT, 67%; c) 7, DMSO, Et3N, RT; d) piperidine, RT; e) 2, DMSO, Et3N, RT, 65% over three steps.