Table 2.

Natriuretic peptides: Effects on mouse atrial myocyte action potentials

	RMP mV	APD90 ms	APD50 ms	Vmax mV/ms
Control	−72.7±0.5	64.9±4.9	22.8±2.3	34.6±0.8
ANP	−72.3±0.5	64.1±4.9	22.1±2.4	34.1±0.8
Control	−73.1±0.4	63.2±3.5	23.0±2.2	33.7±0.6
ANP oligo	−68.7±0.6*	45.4±1.8†	16.7±1.3†	25.9±0.4*
Control	−73.0±0.6	62.8±3.7	23.9±0.4	33.3±0.8
mutANP	−72.0±0.8*	60.6±3.8†	20.8±0.3†	30.5±1.3†
Control	−72.9±0.5	64.7±3.0	24.2±0.2	33.9±0.5
mutANP oligo	−70.7±0.5†	61.4±2.8†	20.7±0.3†	28.6±0.4†
Control	−72.3±1.8	64.8±1.0	23.0±0.8	34.5±1.2
BNP	−71.4±1.3	63.9±1.4	22.1±1.4	33.5±1.3
Control	−72.5±0.5	65.2±3.0	23.7±0.3	34.4±0.7
BNP oligo	−69.7±0.6†	60.2±3.0†	19.7±0.3†	30.7±1.0†

oligo represents oligomer

^*P<0.05

^†P<0.01; n=8-12

Initial peptide concentration = 500 nM