Figure 3. Schematic representation of microautophagy:

Bulk of proteins and cells components such as organelles (1. In bulk) can be integrated into lysosomes and late endosomes directly through invaginations at the lysosomal membrane. Cytosolic proteins targeted by Hsc70 can be also selectively degraded by its internalization into late endosome invaginations in a process known as Endosomal microautophagy (2).