Table 1.
Symptoms, clinical, radiological features, treatments, and outcomes of the pediatric patients.
| Parameter | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 |
|---|---|---|---|---|---|
| Demographic | |||||
| Age (years) | 14 | 1 | 7 | 2 | 10 |
| Gender | Female | Male | Female | Male | Male |
| Comorbidity | AML, septic shock, systemic fungal infection | AML, hypovolemic shock, gastroenteritis | Ewing's sarcoma, superior vena cava syndrome, sepsis | AML, sepsis | AML, sepsis, MISC, systemic fungal infection |
| Presenting symptoms, clinical, and radiological features | |||||
| Fever | + | + | + | + | + |
| Cough | + | – | – | – | – |
| Diarrhea | – | – | – | + | – |
| Nausea | + | – | – | – | – |
| Vomiting | + | – | – | – | – |
| Myalgia | – | + | + | + | + |
| Hematochezia | – | + | – | – | – |
| Hematemesis | – | + | – | – | – |
| Melena | – | + | – | – | – |
| Abdominal pain | – | – | + | – | – |
| Anorexia | – | – | + | – | – |
| Chest X-ray | No abnormality detected | Pneumonia | Right pleura effusion, pneumonia | Pneumonia | No abnormality detected |
| Treatment | Chemotherapy (cytarabine, carboplatin, etoposide, methotrexate), dexamethasone, ceftazidime, IV meropenem, IV imipenem-cilastatin, favipiravir, IV remdesivir |
TC and PRC transfusion | Dexamethasone, methylprednisolone, amlodipine, furosemide, lovenox, meropenem, metronidazole, cefepime, ceftriaxone, remdesivir |
Chemotherapy, dexamethasone, TC transfusion, amikacin, metronidazole, fluconazole, ceftazidime, meropenem, tygacil, cefotaxime, cefepime, remdesivir |
Chemotherapy, morphine, sertraline, TC and PRC transfusion, mycamine, amphotericin B, methylprednisolone, dexamethasone, lovenox, meropenem, levofloxacin, ceftazidime, favipiravir, acyclovir, IVIG |
| Outcome | Discharged | Fatal | Fatal | Fatal | Fatal |
AML, acute myeloid leukemia; IV, intravenous; IVIG, intravenous immunoglobulin; MISC, multisystem inflammatory syndrome; PRC, packed red cells; TC, thrombocyte concentrates.