Table 3.

List of shared active mutation sites of the five pediatric cases with base composition in percentage of total reads.

Gene	Position	Base	Case
			1	2	3	4	5
nsp2	1613	A	0	70.7	0.1	97.4	0
		T	0	0	0.1	0	0
		G	0	0	0.1	0	0
		C	100	29.3	99.8	2.6	100
		Depth	10,346	1,078	1,992	114	10,139
nsp4	9565	A	0	0	0	0	0
		T	83.5	48.0	94.1	99.9	79.9
		G	0	0	0	0	0
		C	16.5	52.0	5.9	0.1	20.1
		Depth	13,893	13,253	6,656	18,554	15,709
nsp6	11286	A	1.7	3.1	3.3	1.4	2.0
		T	94.9	90.5	90.9	96.3	94.0
		G	3.4	6.4	5.7	2.3	4.0
		C	0	0	0	0	0
		Depth	20,745	12,194	9,999	36,273	20,443
nsp6	11287	A	4.3	8	7.7	2.8	5.1
		T	2.1	3.5	3.7	1.8	2.3
		G	93.6	88.6	88.6	95.4	92.6
		C	0	0	0	0	0
		Depth	20,788	13,500	10,009	36,375	20,462
nsp6	11511	A	0	0	0	0	0
		T	0	20.4	0	27.1	0
		G	0	0	0	0	0
		C	100	79.6	100	72.9	99.9
		Depth	14,116	2,010	6,557	48,036	10,454
ORF8	28254	A	93.0	94.6	94.2	95.2	96.5
		T	0.1	0	0	0	0
		G	0.0	0	0	0	0
		C	3.3	1.4	1.4	3.7	1.5
		Dela	3.7	4.0	4.4	1.1	2.0
		Depth	17,168	4,656	5,297	82,051	20,152

^aDel, base deletion.