Table 3.

5-HTTLPR/rs25531 Genotype and Inertia Regarding Depression and Anxiety, results of Multilevel Regression [with t affect scale as response variable and t−1 affect scale, dummy-coded genotype information, and their interaction as predictors]

	Random intercept model			Random slope model
	b	95% CI		b	95% CI
Intercept PROMIS depression
Value	5.519	1.561	9.477	5.467	1.506	9.428
Genotype	0.877	− 0.344	2.098	0.927	− 0.297	2.151
Age	− 0.096	− 0.305	0.114	− 0.096	− 0.305	0.113
Female	2.254	1.185	3.324	2.321	1.253	3.390
Weekend	− 0.275	− 0.554	0.003	− 0.232	− 0.475	0.011
Slope PROMIS depression
Value	0.579	0.186	0.971	0.263	0.040	0.487
Genotype	0.009	− 0.082	0.100	− 0.016	− 0.074	0.043
Age	− 0.023	− 0.044	− 0.002	− 0.008	− 0.021	0.004
Female	0.177	0.082	0.273	0.137	0.074	0.200
Intercept PROMIS anxiety
Value	5.012	1.658	8.367	4.986	1.615	8.358
Genotype	0.922	− 0.016	1.859	0.954	0.013	1.895
Age	− 0.090	− 0.269	0.090	− 0.089	− 0.269	0.091
Female	1.509	0.710	2.309	1.546	0.744	2.348
Weekend	− 0.245	− 0.489	− 0.002	− 0.243	− 0.467	− 0.019
Slope PROMIS anxiety
Value	0.171	− 0.149	0.491	0.153	− 0.078	0.383
Genotype	0.085	0.005	0.165	0.019	− 0.038	0.076
Age	− 0.003	− 0.019	0.014	− 0.003	− 0.016	0.009
Female	0.133	0.053	0.213	0.077	0.022	0.132

Week/weekend is included as level 1 covariate, age and sex are included as level 2 covariates. The Intercept sections show the main effect of covariates on affect scores, which is the effect of the covariate if all other covariates were held at zero. The Slope sections show the effect of the covariate on the slope of the t−1 affect score, i.e. the regression coefficients of the interaction between covariate and person mean-centered t−1 affect score in predicting t affect score

b regression coefficient, CI confidence interval