Table 2.

List of CQs and members in charge

Epidemiology/pathophysiology

CQ1. What is the pathophysiology of primary sclerosing cholangitis? (Tazuma)

CQ2. What is the epidemiology of primary sclerosing cholangitis? (Tanaka)

CQ3. What are the features of primary sclerosing cholangitis in Japan? (Tanaka)

CQ4. What are the risk factors of primary sclerosing cholangitis? (Tazuma)

Diagnostics

CQ5. What are the symptoms that suggest primary sclerosing cholangitis? (Isayama)

CQ6. What are the characteristic blood test findings for primary sclerosing cholangitis? (Nakazawa)

CQ7. What are the diagnostically useful imaging findings for primary sclerosing cholangitis? (Nakazawa)

CQ8. On what type of cases is endoscopic retrograde cholangiopancreatography (ERCP) performed? (Nakazawa)

CQ9. Is liver biopsy useful for the diagnosis of primary sclerosing cholangitis? (Notohara)

CQ10. How is this disease differentiated from cholangiocarcinoma and how are complications diagnosed? (Tsuyuguchi)

Therapy

CQ11. What pharmacotherapies are effective? (Isayama)

CQ12. How is itching treated? (Isayama)

CQ13. What are the indications for and methods of utilizing biliary drainage? (Tsuyuguchi)

CQ14. What is the optimal timing and indications for liver transplantation (Kokudo)

Prognosis

CQ15. What is the prognosis for primary sclerosing cholangitis? (Tanaka)

CQ16. What are the complications associated with primary sclerosing cholangitis? (Tsuyuguchi)