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. 2022 Mar 4;13:856803. doi: 10.3389/fphys.2022.856803

Table 1.

Summary of 5th edition of WHO updates compared to the previous edition (4th edition).

WHO 4th Edition WHO 4th Edition
Oncocytic variant of IPMN IOPN is now considered a separate entity
ITPN was considered a variant of IPMN ITPN is now considered a separate entity
Three-tiered dysplasia grading system
  • Low-grade

  • Intermediate

  • High-grade

Two-tiered dysplasia grading system
  • Low-grade (original intermediate grade is part of the spectrum of low-grade dysplasia)

  • High-grade