Table 2.
Associations between FTSE100 and structural characteristics of the fear network: cortical and subcortical volumes. Day/MonthAVG data averaged over days and months. Intracranial volume (ICV) was selected as a reference measure, which was not expected to exhibit significant associations with global stock market behaviour. βstd standardized β coefficients, pfdr p-values corrected for multiple testing with false discovery rate. The analyses leveraged random linear mixed effects framework with subject as a random effect, as a subset (n = 1427) of the study subjects was scanned twice. *corresponding effect sizes estimated with the mutual information criterion are reported in the supplement (Supplementary Table S11).
| Region | Linear mixed-effects | Effect-sizes*, Pearson r (95% CI) | ||||
|---|---|---|---|---|---|---|
| βstd | T883 | pfdr | Raw, n = 30,775 | DayAVG, n = 1299 | MonthAVG, n = 66 | |
| L amygdala | − 0.054 | − 9.51 | < 0.001 | − 0.055 (− 0.066, − 0.043) | − 0.253 (− 0.304, − 0.202) | − 0.615 (− 0.746, − 0.439) |
| R amygdala | − 0.062 | − 10.91 | < 0.001 | − 0.063 (− 0.074, − 0.052) | − 0.282 (− 0.332, − 0.231) | − 0.644 (− 0.767, − 0.477) |
| L accumbens | − 0.054 | − 9.54 | < 0.001 | − 0.055 (− 0.066 ,− 0.044) | − 0.232 (− 0.283, − 0.18) | − 0.623 (− 0.752, − 0.449) |
| R accumbens | − 0.062 | − 10.89 | < 0.001 | − 0.064 (− 0.075, − 0.052) | − 0.259 (− 0.309, − 0.207) | − 0.662 (− 0.779, − 0.5) |
| L LOFC | − 0.026 | − 4.68 | < 0.001 | − 0.031 (− 0.042, − 0.02) | − 0.141 (− 0.193, − 0.087) | − 0.443 (− 0.619, − 0.225) |
| R LOFC | − 0.019 | − 3.49 | 0.001 | − 0.023 (− 0.034, − 0.012) | − 0.082 (− 0.136, − 0.028) | − 0.292 (− 0.499, − 0.054) |
| L insula | 0.037 | 6.62 | < 0.001 | 0.042 (0.031, 0.053) | 0.21 (0.157, 0.261) | 0.494 (0.286, 0.657) |
| R insula | 0.032 | 5.86 | < 0.001 | 0.037 (0.026, 0.048) | 0.187 (0.134, 0.239) | 0.413 (0.19, 0.595) |
| L subcallosal | 0.018 | 3.18 | 0.002 | 0.02 (0.009, 0.032) | 0.134 (0.08, 0.187) | 0.322 (0.087, 0.524) |
| R subcallosal | 0.015 | 2.74 | 0.008 | 0.019 (0.007, 0.03) | 0.129 (0.075, 0.182) | 0.305 (0.068, 0.509) |
| L anterior cingulate | 0.025 | 4.67 | < 0.001 | 0.035 (0.024, 0.046) | 0.178 (0.124, 0.23) | 0.408 (0.184, 0.591) |
| R anterior cingulate | 0.024 | 4.44 | < 0.001 | 0.033 (0.022, 0.044) | 0.169 (0.116, 0.222) | 0.428 (0.207, 0.607) |
| L paracingulate | 0.004 | 0.8 | 0.426 | 0.001 (− 0.01, 0.013) | 0.044 (− 0.01, 0.098) | 0.106 (− 0.14, 0.339) |
| R paracingulate | 0.005 | 0.83 | 0.426 | 0.003 (− 0.008, 0.014) | 0.052 (− 0.003, 0.106) | 0.122 (− 0.124, 0.353) |
| Intracranial volume | 0.004 | 0.87 | 0.426 | − 0.009 (− 0.02, 0.002) | − 0.016 (− 0.07, 0.038) | − 0.098 (− 0.332, 0.147) |