Table 2.
Respiratory mechanics of forty-two COVID-19 patients and forty-three non-COVID-19 patients with acute respiratory distress syndrome.
| Parameters | COVID-19 patients with ARDS (n = 42) | Non-COVID-19 patients with ARDS (n = 43) | P-value |
|---|---|---|---|
| Ventilatory parameters | |||
| Tidal volume (ml/kg) of PBW | 5.9 ± 0.04 | 6.1 ± 0.06 | 0.71 |
| Respiratory rate (cycles/min) | 30.8 ± 0.56 | 28.2 ± 0.62 | 0.003* |
| Positive-end-expiratory-pressure (cm H2O) | 10.6 ± 0.25 | 12.2 ± 0.42 | 0.002* |
| PaO2/FiO2 ratio | 115.3 ± 5.03 | 144.7 ± 5.32 | 0.001* |
| PaO2/FIO2 <100, n (%) | 16 (38) | 26 (41) | 0.01* |
| PaO2/FIO2 ≥ 100, n (%) | 26 (62) | 37 (59) | |
| Respiratory system compliance (ml/cm H2O) | 45.0 ± 0.50 | 45.6 ± 0.55 | 0.46 |
| Respiratory system resistance (cm H2O/l/s) | 15.5 ± 0.31 | 15.1 ± 0.44 | 0.45 |
| Recruitment-to-inflation ratio | 0.49 ± 0.02 | 0.55 ± 0.02 | 0.04* |
| Ventilatory ratio | 1.87 ± 0.05 | 1.62 ± 0.03 | 0.001* |
| Plateau pressure (cm H2O) | 23.8 ± 0.35 | 25.1 ± 0.33 | 0.01* |
| Driving pressure (cm H2O) | 10.1 ± 0.16 | 10.1 ± 0.21 | 0.85 |
PaO2/FiO2 ratio, partial arterial pressure of oxygen to fractional inspired concentration of oxygen ratio, Ventilatory ratio = [minute ventilation (ml/min) × PaCO2 (mmHg)]/(predicted body weight ×100 ×37.5), Driving pressure = plateau pressure – PEEP.
*
P-values ≤ 0.05 were statistically significant (comparisons between the COVID-19 vs. the non-COVID-19 group of patients).