Table 6.
Univariate and multivariate logistic regression analysis of predictors of 60-day mortality in eighty-five COVID-19 and non-COVID-19 patients with acute respiratory distress syndrome.
| Characteristic | Univariate odds ratio (95% CI)† | p-value | Model 1 odds ratio (95% CI)† | P-value |
|---|---|---|---|---|
| APACHE II | 3.31 (1.87–5.87) | <0.001* | ||
| Non-COVID-19 ARDS | 0.29 (0.10–0.85) | 0.024* | 1.08 (0.06–19.22) | 0.05* |
| Respiratory compliance, ml/cm H20 | 0.82 (0.69–0.97) | 0.021* | 0.65 (0.41–1.04) | 0.07 |
| Ventilatory ratio, per 0.10 units | 3.03 (1.79–5.11) | <0.001* | 3.67 (1.61–8.35) | 0.002* |
| PaO2/FiO2 ratio | 0.97 (0.96–0.99) | <0.001* | 0.93 (0.87–0.99) | 0.02* |
| D-Dimer (mcg/ml, normal: <1) | 1.84 (1.40–2.43) | <0.001* | ||
| Interleukin-6 (pg/ml, normal: 1–7) | 1.01 (1.00–1.01) | 0.001* |
APACHE II score, Acute Physiology and Chronic Health Evaluation II score; PaO2/FiO2 ratio, partial arterial pressure of oxygen to fractional inspired concentration of oxygen ratio. Ventilatory ratio = [minute ventilation (ml/min) × PaCO2 (mmHg)]/(predicted body weight ×100 ×37.5).
*
P-values <0.05 were statistically significant (comparisons between the COVID-19 vs. the non-COVID-19 group of patients).
†
CI indicates the 95% confidence interval.