Table 1.

Statistical analysis of MCHR1 in the presence of different MRAP2 mutants in response to MCH.

Data statistics of Figures 6A–H	LogEC50	p-value comparison
		vs. receptor alone	vs. MRAP2 WT
MCHR1 alone	−8.149 ± 0.10	–	<0.0001
MCHR1:MRAP2 WT	−7.061 ± 0.40	<0.0001	–
MCHR1:MRAP2 Δ4–11	−7.242 ± 0.19	<0.0001	<0.0001
MCHR1:MRAP2 Δ12–25	−6.765 ± 1.15	<0.0001	0.9803
MCHR1:MRAP2 Δ26–35	−7.551 ± 0.31	<0.0001	<0.0001
MCHR1:MRAP2 Δ36–45	−6.643 ± 0.43	<0.0001	0.8704
MCHR1:MRAP2 Δct	−7.515 ± 0.54	<0.0001	<0.0001
MCHR1:MRAP2 t97	−7.338 ± 0.68	<0.0001	<0.0001
MCHR1:MRAP2 t118	−7.593 ± 0.63	<0.0001	<0.0001
MCHR1:MRAP2 t143	−7.599 ± 0.46	<0.0001	<0.0001

Values were expressed as the mean ± S.E.M. of at least three independent experiments. Two-way ANOVA with Tukey post-test was applied in the statistical analysis.