Table 5.
Factors | Number of cases | Median PFS (m) | 95% CI | p-value |
---|---|---|---|---|
Age (year) | ||||
<65 | 241 | 41 | 38.170–43.830 | 0.006 |
≥65 | 140 | 35 | 28.418–41.582 | |
Gender | ||||
Male | 225 | 39 | 35.989–42.011 | 0.163 |
Female | 156 | 37 | 31.419–42.581 | |
Albumin (g/L) | ||||
<35 | 149 | 37 | 32.588–41.412 | 0.004 |
≥35 | 232 | 44 | 40.498–47.502 | |
β2-MG (mg/ml) | ||||
<3.5 | 174 | 46 | 42.116–49.884 | 0.001 |
3.5 ≤ β2-MG < 5.5 | 86 | 43 | 38.796–47.204 | |
≥5.5 | 121 | 35 | 30.211–39.789 | |
LDH (U/L) | ||||
<245 | 142 | 43 | 39.976–46.024 | 0.105 |
≥245 | 239 | 40 | 36.808–43.192 | |
P53 | ||||
Deletion | 75 | 42 | 34.773–49.227 | 0.042 |
Nondeletion | 306 | 41 | 38.809–43.191 | |
RB1 | ||||
Deletion | 61 | 40 | 32.119–47.881 | 0.167 |
Nondeletion | 320 | 41 | 38.743–43.257 | |
1q21 | ||||
Amplification | 58 | 40 | 34.995–45.005 | 0.536 |
Nonamplification | 323 | 41 | 38.813–43.187 | |
IGH | ||||
Rearrangement | 67 | 30 | 12.078–47.922 | <0.001 |
Nonrearrangement | 314 | 42 | 39.948–44.052 | |
ADC value (×10−3 mm2/s) | ||||
ADC < 0.4 | 22 | 48 | 39.468–56.532 | <0.001 |
0.4 ≤ ADC < 0.6 | 60 | 53 | 48.202–57.798 | |
0.6 ≤ ADC < 0.8 | 92 | 43 | 39.518–46.482 | |
0.8 ≤ ADC < 1.0 | 99 | 33 | 28.542–37.458 | |
1.0 ≤ ADC < 1.2 | 74 | 29 | 25.607–32.393 | |
ADC ≥ 1.2 | 34 | 21 | 17.757-24.243 |