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. 2022 Mar 8;119(11):e2119415119. doi: 10.1073/pnas.2119415119

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Copyright © 2022 the Author(s). Published by PNAS.

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Fig. 3. — ZFP961 potentially inhibits HIV-1 (PBS-Lys) pseudovirus infection. (A and B) FACS (fluorescence-activated cell sorting) analysis to calculate pSicoR-RFP pseudovirus (A) and pNL4.3-RFP pseudovirus (B) infection rates in HEK293T cells overexpressing GFP-tagged ZFP961, ZFP961mut, or ZFP809, as well as in Zfp961 WT and KO mESCs. (C and D) FACS analysis (Upper) and statistical plot (Lower) for the pSicoR-RFP pseudovirus (A) and pNL4.3-RFP pseudovirus (B) infection rate in mouse PBLs before and after Zfp961 KO. t test: Error bars indicate SD; ***P < 0.001, ****P < 0.0001; n = 6.