Figure 1.
Systemic interactions between age, T cells, and microbiota
The amount of variance in composition of nasal (NAS) and rectal (REC) microbiota and T cell immune populations that are explained by the predictors: preterm birth (gestational age at birth< 37 weeks), postnatal day of life (DOL), postmenstrual age (PMA), T cell population composition, and microbiota composition. Controlling for PMA, system interdependence was diminished but remained highly significant (red). All comparisons control for preterm birth. (∗p < 10−4, ∗∗p < 10−20, multivariate ANOVA).