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. 2022 Mar 4;12:843880. doi: 10.3389/fonc.2022.843880

Table 1.

Expression level of LOX family members between normal tissue and tumor tissue in liver cancer, and overall survival of overexpressing LOX family members in liver cancer.

Gene name Mean TCGA TIMER
Normal tissue group Tumor tissue group P value HR 95%CI P value HR 95%CI P value
LOX 0.418 ± 0.268 1.112 ± 0.898 < 0.001 1.53 1.08-2.16 0.017 1.223 1.073-1.416 0.003
LOXL1 0.540 ± 0.381 1.018 ± 0.944 = 0.001 0.93 0.66-1.32 0.693 0.999 0.897-1.113 0.986
LOXL2 0.623 ± 0.311 1.725 ± 0.735 < 0.001 1.19 0.84-1.68 0.333 1.188 0.984-1.434 0.073
LOXL3 0.312 ± 0.178 0.463 ± 0.300 < 0.001 1.65 1.16-2.35 0.005 1.524 1.059-2.194 0.023
LOXL4 1.307 ± 1.092 2.300 ± 1.625 < 0.001 1.44 1.02-2.05 0.038 1.080 0.980-1.191 0.119