Table 2.
The Cox proportional hazard model of LOX family members and six tumor-infiltrating immune cells in liver cancer (TIMER), and Number of genes that are positively and negative correlated with LOX family members.
| coef | HR | 95%CI_l | 95%CI_u | p.value | sig | Number of positively correlated genes | Number of positively correlated genes | |
|---|---|---|---|---|---|---|---|---|
| B_cell | -7.875 | 0 | 0 | 0.484 | 0.031 | * | ||
| CD8_Tcell | -5.339 | 0.005 | 0 | 0.714 | 0.036 | * | ||
| CD4_Tcell | -4.127 | 0.016 | 0 | 11.792 | 0.220 | |||
| Macrophage | 5.800 | 330.240 | 1.925 | 56641.590 | 0.027 | * | ||
| Neutrophil | -0.054 | 0.947 | 0 | 54322.082 | 0.992 | |||
| Dendritic | 5.245 | 189.571 | 5.129 | 7006.334 | 0.004 | ** | ||
| LOX | 0.087 | 1.091 | 0.919 | 1.296 | 0.321 | 13085 | 6837 | |
| LOXL1 | -0.159 | 0.853 | 0.716 | 1.015 | 0.073 | 12853 | 7069 | |
| LOXL2 | 0.019 | 1.020 | 0.742 | 1.401 | 0.905 | 13393 | 6529 | |
| LOXL3 | -0.022 | 0.979 | 0.446 | 2.148 | 0.957 | 13866 | 6056 | |
| LOXL4 | 0.073 | 1.076 | 0.959 | 1.207 | 0.213 | 11983 | 7939 |
*p < 0.05, **p < 0.01.
95%CI_l: Lower limit of 95% Confidential Interval; 95%CI_u: Upper limit of 95% Confidential Interval.