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. Author manuscript; available in PMC: 2022 Mar 18.
Published in final edited form as: Am J Psychiatry. 2020 Sep 11;178(1):87–98. doi: 10.1176/appi.ajp.2020.19080834

Figure 4. Interpretation of the effect of gene dosage on autism risk.

Figure 4.

Summary interpretation of the differential effects of deletions and duplications on autism risk. Effect-sizes of deletion on most autism specifiers are larger than those of duplications. Duplications and to a lesser extent deletions increase the probability of an autism diagnosis after adjusting for their effect on NVIQ (transparent arrows).