Table I.
Clinicopathological characteristics of subjects.
| Blood | Tissue | ||||
|---|---|---|---|---|---|
|
|
|
||||
| Clinicopathological characteristic | Healthy controls (n=12) | Early CRC (n=22) | Advanced CRC (n=15) | Early CRC (n=5) | Advanced CRC (n=10) |
| Median age, yearsa | 61.5 (55–69) | 64.5 (48–79) | 59 (47–82) | 56 (48–63) | 50.5 (49–75) |
| ≤60 | 6 | 8 | 9 | 4 | 7 |
| >60 | 6 | 14 | 6 | 1 | 3 |
| Sex | |||||
| Male | 8 | 14 | 10 | 3 | 8 |
| Female | 4 | 8 | 5 | 2 | 2 |
| Tumour location | |||||
| Colon | NA | 6 | 6 | 2 | 4 |
| Rectum | NA | 16 | 9 | 3 | 6 |
| TNM stage | |||||
| I/II | NA | 13 | 10 | 3 | 7 |
| III/IV | NA | 9 | 5 | 2 | 3 |
| Serum CEA (ng/ml)a | NA | 2.44 (0.20-38.47) | 5.13 (1.55-113.00)b | 1.11 (0.20-38.47) | 5.00 (1.55-113.00) |
| WBC count (×109 cells/l)a | 5.44 (3.67-8.59) | 5.58 (2.78-12.00) | 5.92 (3.92-10.00) | 4.94 (4.79-5.77) | 5.90 (3.92-10.00) |
a
Results are presented as the median (minimum-maximum).
b
P<0.05 vs. early CRC. CRC, colorectal cancer; CEA, carcinoembryonic antigen; WBC, white blood cell; TNM, Tumour-Node-Metastasis.