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. 2022 Mar 16;2(1):e31732. doi: 10.2196/31732

Table 2.

Search interest for non-COVID-19 communicable versus noncommunicable term groups in 2020-2021 seasons compared to those seasons in 2011-2019.

Term Seasonalitya P valuesb for test of different search from prior years for each term P valuesc for test of lower search from prior years for each term

P value AtMd, mean (SD) Weeke, circular mean (SD) Spring Summer Autumn Winter Spring Summer Autumn Winter
Communicable and/or acute exposure conditions (non-COVID)

bug bite <.001 0.38 (0.05) 29 (1.2) .54 .43 .06 <.001 .41 >.99 .05 <.001

chicken pox .06 f <.001 <.001 <.001 <.001 <.001 .009 <.001 <.001

chlamydia .83 <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

cold medicine <.001 0.25 (0.04) 51 (21.6) <.001 .003 <.001 <.001 <.001 .004 <.001 <.001

conjunctivitis <.001 0.06 (0.04) 13 (11) <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

ear infection <.001 0.07 (0.05) 4 (18.6) <.001 .05 .001 <.001 <.001 .05 <.001 <.001

fifth disease <.001 0.14 (0.06) 11 (2.5) <.001 .03 .02 <.001 <.001 .03 .02 <.001

german measles .38 .71 .91 .81 .21 .97 .90 .63 .14

gonorrhea .48 <.001 .01 <.001 .02 <.001 .01 <.001 .01

HIV .05 0.02 (0.03) 13 (14.8) <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

hpv .62 <.001 .15 .09 <.001 <.001 .14 .07 <.001

impetigo .03 0.07 (0.06) 35 (11) <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

lice <.001 0.06 (0.05) 35 (9.8) <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

measles .01 0.23 (0.07) 12 (3.6) .10 .01 .06 <.001 .08 .01 .05 <.001

meningitis .62 <.001 .008 <.001 <.001 <.001 .008 <.001 <.001

mononucleosis .25 <.001 .77 .55 <.001 <.001 .75 .44 <.001

mumps .62 .01 .004 .002 <.001 .01 .004 .002 <.001

pertussis .64 <.001 .84 .36 .003 <.001 >.99 .28 .002

pink eye <.001 0.09 (0.06) 9 (17.4) <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

ringworm <.001 0.03 (0.04) 27 (10.6) .04 <.001 <.001 <.001 .03 <.001 <.001 <.001

rubella .01 0.05 (0.05) 12 (14.5) .15 .69 .79 .01 .12 .65 .62 .008

salmonella .62 .25 .45 .43 <.001 .20 >.99 .35 <.001

scabies .11 <.001 .02 <.001 <.001 <.001 .02 <.001 <.001

shingles treatment .19 .15 .47 .33 .93 >.99 >.99 >.99 .62

std .02 0.01 (0.03) 20 (15.9) <.001 <.001 .005 <.001 <.001 <.001 .004 <.001

stomach flu <.001 0.33 (0.06) 3 (1.2) <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

strep throat <.001 0.12 (0.07) 5 (19.9) <.001 <.001 <.001 <.001 <.001 <.001 <.001 <.001

syphilis .88 .22 .81 .36 .93 .17 .78 .29 .70

tuberculosis .05 .53 .04 .74 .02 .40 >.99 .60 .02
Noncommunicable, control conditions (non-COVID)

arthritis .26 <.001 .33 .65 .07 <.001 >.99 >.99 .05

broken bone .23 <.001 .03 .53 .004 <.001 .03 .43 .003

burning eyes >.99 <.001 .002 .04 <.001 >.99 >.99 >.99 >.99

cancer .26 <.001 <.001 .007 <.001 <.001 <.001 .006 <.001

cataracts .97 <.001 .33 .50 .12 <.001 .30 .41 .08

claritin <.001 0.16 (0.06) 18 (3.2) .50 .63 .59 .002 .39 >.99 .46 .002

corneal ulcer .26 .10 .04 .74 .86 .08 .03 .60 .56

diabetes .01 0.02 (0.05) 6 (18.9) <.001 .84 .20 .93 <.001 >.99 .16 .70

diabetic retinopathy .88 .15 .70 .43 .40 .12 >.99 >.99 .26

dry eyes .13 .02 .93 .04 <.001 .02 >.99 >.99 >.99

eczema <.001 0.04 (0.05) 9 (17.2) .30 .19 .04 .003 .24 .18 .03 .002

glaucoma .41 <.001 .42 .36 .03 <.001 .38 .29 .02

heart attack .01 0.04 (0.06) 12 (10) .15 .41 .34 .03 .12 .37 .28 .02

high blood pressure <.001 0.05 (0.04) 5 (13.2) <.001 .91 .66 .29 <001 .89 >.99 .20

itchy eyes <.001 0.1 (0.05) 18 (5.3) <.001 .003 .10 .22 >.99 >.99 >.99 >.99

macular degeneration .78 <.001 .42 .36 .08 <.001 >.99 >.99 .05

memory loss .92 <.001 .81 .79 .93 <.001 >.99 .62 .71

pollen <.001 0.29 (0.07) 17 (1.7) <.001 <.001 <.001 .28 >.99 >.99 >.99 >.99

pregnant .05 .38 .43 .79 .80 .30 .38 .62 .53

red eyes .19 .004 .72 .86 .59 >.99 >.99 .66 .39

sore eyes .83 .51 .22 .04 .12 .39 >.99 >.99 >.99

stroke symptoms <.001 0.09 (0.04) 26 (8) .25 .91 .36 .06 >.99 >.99 >.99 >.99

toothache .62 .06 .41 .13 .34 >.99 .37 .11 .23

aIndicates if the search for the years 2011-2019 shows a significant (P<.05) seasonal trend.

bTwo-sided P values regarding any change in search from prior years for each season.

cOne-sided P values regarding a decrease in search from prior years for each season.

dAtM: amplitude to mean ratio, indicating relative seasonal strength.

eIndicates peak high season.

fNot applicable; AtM and circular mean values are provided only for search terms where statistical evidence of that term being seasonal was found.