Table 3.

Hazard of ASCVD and Global CVD Associated with BAC Presence and Gradation.

	Model 1 HR* (95% CI)	P	Model 2 HR† (95% CI)	p
Hard ASCVD (n=5,059; 155 events)
BAC Presence vs. Absence Model
BAC > 0 mg vs. BAC = 0 mg	1.58 (1.13–2.20)	0.007	1.51 (1.08–2.11)	0.02
BAC Gradation Model
Tertile 1 when BAC is present vs. BAC = 0 mg	1.80 (1.31–2.88)	0.01	1.74 (1.09–2.77)	0.02
Tertile 2 when BAC is present vs. BAC = 0 mg	1.65 (1.03–2.66)	0.04	1.60 (0.99–2.58)	0.05
Tertile 3 when BAC is present vs. BAC = 0 mg	1.27 (0.75–2.17)	0.37	1.24 (0.73–2.11)	0.42
Global CVD (n=5,035; 427 events)
BAC Presence vs. Absence Model
BAC > 0 mg vs. BAC = 0 mg	1.28 (1.04–1.57)	0.02	1.23 (1.002–1.52)	0.048
BAC Gradation Model
Tertile 1 when BAC is present vs. BAC = 0 mg	1.20 (0.87–1.65)	0.27	1.16 (0.84–1.60)	0.37
Tertile 2 when BAC is present vs. BAC = 0 mg	1.41 (1.05–1.90)	0.02	1.38 (1.02–1.85)	0.03
Tertile 3 when BAC is present vs. BAC = 0 mg	1.22 (0.90–1.67)	0.20	1.21 (0.89–1.65)	0.23

^*age, race, education level

^†+ glycemic status, smoking, LDL-C and hypertension

BAC: breast arterial calcification; LDL: low-density lipoprotein; CVD: cardiovascular disease; ASCVD: atherosclerotic cardiovascular disease; HR: hazard ratio.